What is facial mesotherapy? Facial mesotherapy is an injectable treatment that rejuvenates the skin. Simply put, it's a technique that harnesses the power of nourishing ingredients, which are injected directly under the skin. Through multiple painless micro-injuries , a customized cocktail of hyaluronic acid, vitamins, amino acids, antioxidants, and other beneficial ingredients gives your skin everything it needs to be radiant. This process addresses the signs of aging , such as wrinkles and sagging, and also acts preventively against their appearance, thus offering long-term results. It also stimulates the natural production of collagen and elastin (the proteins responsible for firmness and elasticity) and provides firm and youthful skin.
Benefits of facial mesotherapy
Deep hydration
Hyaluronic acid and other moisturizing ingredients retain moisture in the deeper layers of the skin and combat dryness.
Radiant appearance
Mesotherapy enhances the skin's natural glow by improving its tone and texture, providing a bright and refreshed result.
Wrinkle reduction
Mesotherapy stimulates the production of collagen and elastin, thereby smoothing fine lines and wrinkles for a more youthful appearance.
Firming
It is ideal for facial firming, as after several repetitions, it supports the skin from within, improves facial contours, and reduces sagging, offering a firmer appearance.
Antioxidant protection
The antioxidants used in mesotherapy help neutralize free radicals that cause premature skin aging. These valuable ingredients protect cells from oxidative stress, keeping the skin healthy, youthful, and resilient to daily environmental challenges such as pollution and UV radiation.
Prevention
Mesotherapy not only addresses existing signs but also acts preventively by delaying the appearance of new signs of aging.
Minimally invasive option
Mesotherapy is an excellent choice for those who want a solution to improve their appearance without surgery and long recovery times.
Areas of mesotherapy application
It is a versatile treatment that can be applied to various areas and offer benefits depending on the specific needs of each area. Let's look in more detail at the areas where it can be applied:
Types of facial mesotherapy
The beauty of the treatment lies in its customization. Depending on the unique needs of the skin, age, and expectations, the specialized doctor will recommend the ideal treatment for you. Let's look at the most popular types of mesotherapy:
Classic mesotherapy
Classic facial mesotherapy can contain up to 50 different ingredients with the aim of nourishing, restoring, and rejuvenating the skin. Ingredients include hyaluronic acid, multivitamins, peptides, L-carnitine, antioxidants, and plant extracts.
Brightening mesotherapy
Brightening mesotherapy is specifically designed to address discolorations, spots, and uneven melanin distribution. It uses targeted ingredients such as vitamin C, kojic acid, arbutin, and other active brighteners, which are injected directly into the skin. The treatment brightens the skin, reduces melasma, and creates a more even and radiant tone. It is ideal for those who want to treat hyperpigmentation or melasma from sun exposure or intense light.
Autologous PRP mesotherapy
PRP therapy (Platelet-Rich Plasma) is a popular, injectable non-invasive aesthetic treatment that utilizes the power of your own blood, collected through a simple blood draw. Subsequently, through a special process, platelet-rich plasma is separated. This "valuable" ingredient is then administered back into the skin via mesotherapy, activating the natural mechanisms of regeneration and collagen and elastin production. It's like giving your skin an "injection" of rejuvenation from its own cells.
Skinboosters & biorevitalizers
Skinboosters and biorevitalizers are special categories of mesotherapy. Skinboosters, with hyaluronic acid as their main ingredient, offer deep hydration and improve skin texture. Biorevitalizers stimulate the natural production of collagen and elastin, promoting tissue regeneration for long-term anti-aging results.
Skinboosters & biostimulators
Jalupro HMW
A biostimulator with amino acids and hyaluronic acid that enhances collagen production and improves skin texture.
Jalutoxin
Combines the benefits of Jalupro HMW with the muscle-relaxing action of Botox for mild wrinkle smoothing without affecting natural expressions. It also helps regulate oiliness and improve certain types of acne.
Profhilo
A skin booster with a high concentration of hyaluronic acid that deeply moisturizes and provides a natural lifting effect.
Karisma
A unique combination of procollagen, hyaluronic acid, and anti-aging ingredients that stimulates natural collagen production and provides immediate hydration.
Polynucleotides
Biostimulators that stimulate cellular regeneration and remodeling, improving skin quality and texture.
Peptides
Bioactive molecules that stimulate collagen and elastin production, offering anti-aging benefits and improving elasticity.
What is the best mesotherapy?
The truth is, there isn't a single answer. The ideal choice for you depends on a number of factors such as age, skin type and needs, your expectations from the treatment, your history with aesthetic treatments, and in some cases, your lifestyle. For this reason, it is important to consult with a specialized doctor to find the appropriate treatment. See all types in detail and find the ideal one for your needs in our guide to the best mesotherapy .
Injection-free alternative
You can enjoy the benefits of mesotherapy without injections by using Dermapen. Through the microneedling technique, thousands of microscopic channels are created in the skin, allowing for the absorption of nutrients without the use of a needle.
Facial mesotherapy procedure
Step-by-step
Area preparation
Before the treatment begins, an anesthetic cream is applied to the treatment area to ensure the process is almost painless. We wait approximately 45 minutes for the cream to take effect.
Multiple punctures
Once the area is ready, the doctor uses a special very thin needle to make many small punctures on the skin's surface to inject the personalized mesotherapy cocktail. The procedure is brief and lasts approximately 15 minutes.
Immediately after treatment
Sunscreen and a regenerative cream are applied to address any irritation and protect the skin. Finally, your doctor will provide appropriate instructions for skin care in the days following the treatment.
Facial mesotherapy results
Every person is different, and so are the results they will experience. For some, results may be visible in a few days, while for others, several sessions may be needed. It depends on skin type and age. Generally, you can expect a gradual improvement in your skin's appearance, which gets even better after a few sessions. The best result is achieved after a complete cycle of treatments, for which a repeat of the treatment every 2 to 4 weeks is recommended for the first 3 sessions. The frequency of mesotherapy repetitions may vary for each individual, so the doctor will recommend what is appropriate for you.
Personalized approach based on age
Another advantage of mesotherapy is that it can be adapted to the unique needs of each age, offering different benefits depending on the stage your skin is in.
Ages 20-30: Prevention and Radiance
At these ages, the primary focus is prevention. Classic mesotherapy with vitamins and skinboosters offer immediate radiance, deep hydration, and protection against environmental factors. Results are instantly visible and last longer at this age.
Ages 30-40: Regeneration and First Signs of Aging
At these ages, when the first fine lines begin to appear, treatments like Jalupro, Prophilo, and PRP become key players. They actively stimulate collagen production, improve elasticity, and address the initial signs of aging with impressive results.
Ages 45+: Intensive Anti-Aging and Reconstruction
The skin requires more intensive care after 45. Combinations of treatments such as Prophilo with peptides, or PRP with skinboosters offer maximum regenerative action. The goal is to restore lost elasticity, reduce deeper wrinkles, and improve facial contour. The results are impressive but often require more sessions to reach their maximum potential, as well as maintenance.
Adaptation
by skin type
Conclusion Mesotherapy is the ideal choice if you are looking for a solution for natural radiance and rejuvenation without drastic interventions. By using nourishing ingredients such as hyaluronic acid and vitamins, it provides firming, deep hydration and reduces wrinkles, generally improving skin texture. If you're looking for a way to improve the appearance of your skin, book your appointment online with the specialized team at Facemed Clinic.
How often is facial mesotherapy performed?
We usually start with 3 sessions that are performed at intervals of approximately 2-4 weeks to boost the desired outcome. This trio of treatments can be repeated twice a year. Another very popular treatment regimen is the application of mesotherapy every 2-3 months. The intervals may seem frequent, but skin nourishment and toning is a continuous need that you need to take care of, which you achieve with the treatment.
What is the duration of the results in mesotherapy?
On average, the results last from 2 to 4 months. After treatment, the skin gradually absorbs the vitamin-rich material that was applied and is revitalized.
Does mesotherapy hurt?
Before starting the treatment, we use an anesthetic cream to significantly reduce pain. So we can say that it is an almost painless treatment and reactions vary depending on the individual and the application area. In addition, the irritation caused by the procedure is minimal and subsides within a few hours.
Is mesotherapy only for the face or also for other areas?
In addition to the face, it can also be applied to body areas that need it. Areas such as the neck, décolletage, and hands are often neglected and show signs of aging and lose their firmness. In our usual practice, we also perform mesotherapy on these areas if needed. Specifically for the neck, skinboosters seem to be an ideal choice.
What do I need to be careful about after mesotherapy?
After the treatment, it is important to use high-protection sunscreen as the skin may be more sensitive to sun exposure. For the first 24 hours, avoid intense exercise, sauna, and frequent touching of the area to prevent irritation. Ideally, do not use makeup for 12-24 hours and make sure to moisturize your skin with appropriate products that promote healing. Your doctor will inform you about any special care you may need after the treatment. You can find detailed information here about what to watch out for after mesotherapy .
Does mesotherapy have side effects?
Generally, we could say that this is one of the safest treatments, provided that certified materials are used by a specialized professional. The most common undesirable side effect is the appearance of a bruise at one of the application sites, which subsides within a few days and can be easily covered with makeup products.

