What is hyaluronidase and when is it used?

Have you heard about hyaluronidase and wondered what exactly this substance is? If you're interested in aesthetic treatments or have had some done with hyaluronic acid, it's worth knowing about this important "ally" that can offer solutions when things don't go as expected.

What is hyaluronidase?

Hyaluronidase is an enzyme that breaks down hyaluronic acid, a natural substance found abundantly in our body and particularly in the skin. It works as an "antidote" to hyaluronic acid injections, since it can dissolve hyaluronic fillers that are widely used in aesthetic treatments.

Think of hyaluronidase like a special key that unlocks and breaks down hyaluronic acid molecules, allowing them to dissolve much faster than would happen naturally.

Actually, our body naturally produces hyaluronidase, but in small amounts that serve the normal metabolism of hyaluronic acid. In the medical field, we use synthetic forms of it for specific therapeutic purposes.

How is hyaluronidase used?

The main use of hyaluronidase in aesthetic medicine is for correcting unwanted results from hyaluronic acid injections. Specifically:

Correcting asymmetries: When fillers have been placed unevenly or asymmetrically and create a result that isn't harmonious on the face.
Managing complications: In cases of vascular occlusion (when filler blocks blood flow), hyaluronidase can serve as emergency treatment for the problem.
Smoothing excessive amounts: When more hyaluronic acid has been used than desired and creates an unnatural result or the so-called "pillow face."
Speeding up absorption: To accelerate the natural process of filler absorption by the body when you're not satisfied with the result.
Addressing Tyndall effect: To correct the blue-gray discoloration that can appear when hyaluronic acid is placed too superficially under the skin.

The results of hyaluronidase

The results of hyaluronidase can be impressively fast, which makes it valuable in emergency situations. Within a few hours, usually in 24-48 hours, the volume from hyaluronic acid can be significantly reduced. What you need to know is that:

There's a chance you might need more than one session for the ideal result, especially if the hyaluronic acid used was high density.
Hyaluronidase will break down both the artificial hyaluronic acid and the natural hyaluronic acid in the area, so it must be used carefully.
The result is permanent, since the hyaluronic acid that breaks down doesn't reappear, but the skin's natural hyaluronic acid will regenerate over time.

Is hyaluronidase safe to use?

Like any medical intervention, hyaluronidase use has both benefits and potential risks. It's generally safe when administered by a specialized doctor, but it can cause:

Temporary swelling or redness in the injection area
Minor bruises or hematomas
Temporary pulling sensation in the skin as the hyaluronic acid breaks down
In rare cases, allergic reactions that can range from mild to severe

That's why it's important to do an allergy test before the full treatment, especially if you have a history of allergies.

When to choose hyaluronidase treatment

Are you thinking whether hyaluronidase is right for you? You can have the treatment in consultation with a specialized doctor, in case you:

Are not satisfied with the result from previous hyaluronic acid treatment
Notice asymmetry or excessive volume after hyaluronic acid treatment
Have developed complications like persistent swelling, blue discoloration or other aesthetic problems
Need emergency treatment for vascular occlusion

Ask the doctos

Dr. Dimitroulas Nikolaos, Doctor

21 0692 9999

Conclusion

Hyaluronidase works as an "antidote" for hyaluronic acid and can prove very useful in certain cases. Remember that it should mainly be used only when necessary. It's not a routine solution but an important option in cases that need correction or managing complications.

It's important to consult with an experienced aesthetic doctor at Facemed Clinic who can understand your needs and evaluate whether hyaluronidase is the right choice for your case.