What is Profhilo® and how does it differ from traditional fillers Profhilo® represents a new category of aesthetic treatments that bridges the gap between mesotherapy and fillers. Unlike conventional fillers that add volume to specific areas, Profhilo® acts as a "cell activator" that spreads naturally within the skin. Its unique composition includes 64mg of pure hyaluronic acid per 2ml, combining high and low molecular weight hyaluronic acid. This combination was created through NAHYCO technology, which allows the product to be stabilized without the use of chemical cross-linking agents.
The science behind bio-remodeling
When Profhilo® is injected into the skin, it works in two phases:
First phase
Immediate hydration
Provides intense hydration to the deeper layers of the skin, restoring moisture lost over time.
Second phase
Bio-stimulation
It stimulates cell receptors, activating the production of four different types of collagen and elastin. This process drastically improves the quality of skin tissues.
The benefits of Profhilo
Deep hydration
The hyaluronic acid in Profhilo can hold up to 1,000 times its weight in water. This means the skin receives intensive hydration that lasts for months.
Natural toning and tightening
Unlike fillers that may alter your natural features, Profhilo improves your skin's elasticity and firmness, while maintaining natural expressiveness.
Improved texture and radiance
The stimulation of collagen production leads to smoother skin with a natural glow. Minor imperfections are smoothed out and the overall skin quality improves.
Long-lasting results
Profhilo results typically last 6-12 months, as the production of new collagen continues for weeks after the treatment.
Profhilo application areas
Face
Cheeks and jawline area: Improves firmness and restores lost volume. Eye area: Reduces fine lines and improves elasticity. Mouth area: Smooths expression lines.
Neck and décolletage
Areas often neglected but which show age. Profhilo significantly improves texture and firmness in these sensitive areas.
Hands
Hands are among the first areas to show signs of aging. Profhilo restores elasticity and improves the appearance of veins and age spots.
Body (Profhilo Body)
The body version is ideal for areas such as upper arms, abdomen, knees, and chest.
Preparation before Profhilo treatment
Preparation timeline
Two weeks before treatment:
Do not use retinoid products (retinol, tretinoin). Avoid AHA/BHA acids (glycolic, salicylic). Limit high-concentration Vitamin C. Avoid exfoliating treatments.
One week before:
Do not have other facial treatments. Avoid waxing in the treatment area. Limit sun exposure and solarium.
48 hours before:
Limit alcohol consumption. Avoid anticoagulant medications (unless medically advised). Try to avoid intense exercise.
On the day of treatment:
Avoid creams or serums. Do not apply perfumes or deodorants to the area.
Treatment Process
Preparation
Preparation
Before the treatment, a detailed skin assessment is performed to determine the appropriate treatment plan. The area is carefully cleansed, and a topical anesthetic cream may be applied for greater comfort.
The BAP (Bio Aesthetic Points) Technique
The BAP (Bio Aesthetic Points) Technique
Profhilo is applied using the special BAP technique, where the product is injected into 5 specific points on each side of the face. These points have been scientifically selected to allow for optimal diffusion of the product.
Duration and frequency
Session duration
15-30 minutes
Recommended course
2 sessions with a 4-week interval
Maintenance
One session every 6-9 months
Profhilo Side Effects: What You Should Know
- Profhilo is considered one of the safest cosmetic treatments, thanks to its natural composition and the absence of chemical cross-linking agents. However, as with any injectable treatment, some mild side effects may occur.
Common Side Effects (temporary)
Redness
May last 2-24 hours
Mild swelling
Usually subsides within 24-48 hours
Small bruises
Rare and subside in 3-7 days
Sensitivity to touch
Transient sensation during the first few hours
Rare Side Effects
Asymmetrical distribution
Can be corrected with supplementary treatment
Allergic reaction
Extremely rare due to natural composition
When to contact your specialist
While most side effects are normal, you should contact your doctor if you notice: Prolonged swelling lasting more than 48 hours. Severe pain or discomfort. Signs of infection (warmth, increasing redness).
After Profhilo: Results and Aftercare Instructions
The first 24 hours
The first 24 hours
Avoid touching or massaging the area. Do not apply makeup for the first 6 hours. Avoid exposure to high temperatures (sauna, steam room).
The first week
The first week
Use gentle cleansers and moisturizer. Apply SPF 30+ sunscreen daily. Avoid intense exercise that causes excessive sweating. Limit alcohol consumption.
Timeline of results
Week 1-2: Immediate benefits
Increased hydration and radiance. Smoother skin texture. Feeling of firmness.
Week 3-4: Progressive improvement
Reduction of fine lines. Improved elasticity. More even skin tone.
Months 2-3: Maximum results
Improved firmness. Natural rejuvenation. Optimal skin quality.
Tips for long-lasting results
Daily care
Use products with hyaluronic acid
Sun protection
Essential for maintaining results
Healthy lifestyle : Adequate hydration and balanced diet Maintenance : Follow the recommended maintenance schedule
Which criteria to use when choosing a treatment:
- Degree of skin laxity
- Desired result
- Budget and maintenance frequency
Combining treatments can often provide even more comprehensive and long-lasting results. Your specialized doctor will guide you appropriately based on your needs.
Combination treatments with Profhilo
Profhilo is the ideal foundation for comprehensive aesthetic regeneration protocols, enhancing the results of other treatments.
Combination with Botox
Combines revitalization with the reduction of dynamic wrinkles. The improved skin from Profhilo makes the results of Botox look even more natural.
Combination with fillers
Improved skin quality allows for better integration of fillers and can make the results last longer.
Combination with Dermapen
Microneedling enhances the absorption of Profhilo and activates additional collagen production mechanisms for deeper regeneration.
Combination with laser treatments
Fractional laser with Profhilo offers a comprehensive approach, superficial improvement, and deep biological regeneration.
Combination with RF
Radiofrequencies enhance collagen production, complementing the action of Profhilo for even better tightening and lifting.
Combination with PRP
The combination of pure hyaluronic acid with PRP growth factors offers a powerful regenerative action.
Profhilo for different skin types
Each skin type benefits differently from the treatment, but all can experience the benefits.
Oily skin
Profhilo regulates sebum production and reduces the appearance of large pores. The improved texture creates smoother and more balanced skin without additional oiliness.
Dry skin
The intensive hydration provided by hyaluronic acid restores moisture to the deeper layers. It is ideal for dehydrated skin that needs deep nourishment.
Combination skin
The uniform diffusion of Profhilo balances the different needs of each area. It hydrates dry spots and regulates oiliness in the T-zone.
Sensitive skin
The natural composition without chemical additives makes Profhilo particularly safe for sensitive skin, offering gentle but effective regeneration.
Mature skin
It stimulates the natural production of collagen and elastin, which decreases with age, thereby restoring firmness and reducing expression lines.
Conclusion Profhilo is the ideal choice if you are looking for natural skin rejuvenation and want to offer a holistic improvement in its appearance. Thanks to its innovative composition, it achieves gradual and natural results that last, making it ideal for long-term care and anti-aging prevention. Book your appointment at Facemed Clinic and discover the unique benefits of the treatment for yourself.
Cost
Symptoms
- Wrinkles
- Facial sagging
- Body sagging
- Dull skin
Does the procedure hurt?
The procedure is usually well tolerated by most. The sensation is described as a slight sting that lasts a few seconds at each injection site. For greater comfort, a topical anesthetic cream can be applied.
When will I see the first results?
The first signs of improvement (increased radiance and hydration) are visible in 2-3 days. Full results develop gradually and reach their maximum 4-6 weeks after the second session.
What is the price of Profhilo?
The price for Profhilo on the face is 350€ and on the body is 450€.
Is the treatment safe for all skin types?
Profhilo is suitable for all skin types, even darker skin tones, as it does not cause changes in skin pigmentation.

